吴桐

特聘教授、副院长、博导

简介

东华大学与美国佐治亚理工学院联合培养博士，佐治亚理工学院生物医学工程系博士后。入选第六届中国科协青年人才托举工程、山东省泰山学者青年专家、山东省优青、山东省高等学校青创人才引育计划“先进生物材料与再生医学”创新团队负责人，获得中国纺织工业联合会科学技术奖励技术发明二等奖、中国生物医学工程学会优秀博士论文奖，入选英国皇家化学会旗下期刊Nanoscale2023年度新锐科学家（Emerging Investigators）。目前主要从事功能纳米材料、生物医用纺织材料的研发，并应用于药物缓释、组织器官修复和再生医学。研究成果在国际和国内会议报告中多次获奖，并被ChemistryViews突出报道。在Angewandte Chemie International Edition、Chemical Reviews、Materials Today Advances、ACS Applied Materials & Interfaces、Journal of Controlled Release、Advanced Healthcare Materials等期刊发表60余篇高水平论文，包括高被引论文和热点论文一篇，授权9项中国发明专利。目前担任中国生物医学工程学会青年委员，Advanced Fiber Materials、Military Medical Research、《纺织学报》和《精准医学杂志》等杂志的青年编委、英国皇家化学会Nanoscale Horizons Community Board成员以及美国化学会ACS Biomaterials Science & Engineering Early Career Editorial Advisory Board成员，并为中国生物材料学会、中国生物医学工程学会、中国纺织工程学会、中国化学会和美国化学会会员，同时受邀担任多个国际知名期刊的特邀审稿人。

个人主页

ResearchGate: https://www.researchgate.net/profile/Tong_Wu21

Scopus: https://www.scopus.com/authid/detail.uri?authorId=56957431900

Google Scholar: https://scholar.google.co.jp/citations?user=K8W3y2QAAAAJ&hl=en&oi=sra

目前任职

青岛大学神经再生与康复研究院，特聘教授、副院长

青岛大学医学部研究院联合支部，党支书

工作经历

2020.06-至今   青岛大学神经再生与康复研究院，特聘教授

2018.12-2019.12 佐治亚理工学院，博士后研究员

研究领域

医用生物材料、纺织材料、功能纳米纤维、药物缓释、干细胞行为调控、组织修复、再生医学

已发表学术论文 (#一作，*通讯)

【27】Y. Liu, L. Xie, M. Gao*, R. Zhang, J. Gao, J Sun, Q. Chai, T. Wu, K. Liang, P. Chen, Q. Wan*, B. Kong*, Super-Assembled Periodic Mesoporous Organosilica Frameworks for Real-Time Hypoxia-Triggered Drug Release and Monitoring. ACS Applied Materials & Interfaces, 13 (2021), 50246−50257.

【26】Q. Chai, L. Xie, M. Gao*, Y. Liu, X. Xu, X. Huang, P. Chen, T. Wu, Q. Wan*, Biao Kong*, Super-assembled Silica Nanoprobes for Intracellular Zn(II) Sensing and Reperfusion Injury Treatment through in situ MOF Crystallization. Analyst, (2021), DOI: 10.1039/d1an01475g.

【25】S. Shen*, T. Wu*, J. Xue, H. Li, H. Cheng, Q. Chen, L. Wu, J. Qian*, A Smart Material Built upon the Photo-Thermochromic Effect and its Use for Managing Indoor Temperature. Chemical Communications, 57 (2021), 8628-8631.

【24】Z. Feng^#, X. Zhang^#, N. Liu^#, Y. Wang, Z. Zhou, O. O. Glebov, T. Wu*. Promotion of Neurite Outgrowth and Extension Using of Injectable Welded Nanofibers. Chemical Research in Chinese Universities, 37 (2021), 522-527. (Invited article)

【23】Y. Wang, T. Wu*, J. Zhang, Z. Feng, M. Yin*, X. Mo*. A Bilayer Vascular Scaffold with Spatially Controlled Release of Growth Factors to Enhance In-Situ Rapid Endothelialization and Smooth Muscle Regeneration. Materials & Design, 204 (2021), 109649. IF=6.289.

【22】J. Qiu,^# M. Xie,^# T. Wu^#, D. Qin, Y. Xia. Gold Nanocages for Effective Photothermal Conversion and Related Applications. Chemical Science, 11 (2020), 12955-12973. (Equal Contribution), IF=9.346

【21】D. Li, L. Tao, T. Wu, L. Wang, B. Sun, Q. Ke, X. Mo, B. Deng. Mechanically-Reinforced 3D Scaffold Constructed by Silk Nonwoven Fabric and Silk Fibroin Sponge. Colloids and Surfaces B: Biointerfaces, 196 (2020): 111361. IF=4.389

【20】J. Xue, T. Wu, J. Qiu, Y. Xia. Spatiotemporally Controlling the Release of Biological Effectors Enhances Their Effects on Cell Migration and Neurite Outgrowth. Small Methods, 4 (2020), 2000125. IF=12.13

【19】J. Xue, T. Wu, J. Qiu, S. Rutledge, M. L. Tanes, Xia, Y. Promoting Cell Migration and Neurite Extension along Uniaxially Aligned Nanofibers with Biomacromolecular Particles in a Density Gradient. Advanced Functional Materials, 30 (2020), 2002031. IF=16.836

【18】T. Wu, J. Xue, Y. Xia. Engraving the Surface of Electrospun Microfibers with Nanoscale Grooves Promotes the Outgrowth of Neurites and the Migration of Schwann Cells. Angewandte Chemie International Edition, 59 (2020), 15626-15632. IF=12.959

【17】T. Wu, X. Mo, Y. Xia. Moving Electrospun Nanofibers and Bioprinted Scaffolds toward Translational Applications. Advanced Healthcare Materials, 9 (2020), 1901761. IF = 6.27

【16】 H. Li,^# T. Wu^#, J. Xue, Q. Ke, Y. Xia. Transforming Nanofiber Mats into Hierarchical Scaffolds with Graded Changes in Porosity and/or Nanofiber Alignment. Macromolecular Rapid Communications, 41 (2020), 1900579. (Equal Contribution). Selected by “Best of Healthcare from Macromolecular Rapid Communications”. IF=4.078

【15】T. Wu, H. Li, J. Xue, X. Mo, Y. Xia. Photothermal Welding, Melting, and Patterned Expansion of Nonwoven Mats of Polymer Nanofibers for Biomedical and Printing Applications. Angewandte Chemie International Edition, 58 (2019), 16416-16421. Highlighted on ChemViews, IF=12.257

【14】J. Xue^#, T. Wu^#, Y. Dai^#, Y. Xia. Electrospinning and Electrospun Nanofibers: Methods, Materials, and Applications. Chemical Reviews, 119 (2019), 5298-5415. (Equal Contribution). Hot Paper & Highly Cited Paper, IF=54.301

【13】T. Wu, H. Li, M. Xie, S. Shen, W. Wang, M. Zhao, X. Mo, Y. Xia. Incorporation of Gold Nanocages into Electrospun Nanofibers for Efficient Water Evaporation through Photothermal Heating. Materials Today Energy, 12 (2019), 129-135.

【12】T. Wu, J. Xue, H. Li, C. Zhu, X. Mo, Y. Xia. General Method for Generating Circular Gradients of Active Proteins on Nanofiber Scaffolds Sought for Wound Closure and Related Applications, ACS Applied Materials & Interfaces, 10 (2018), 8536-8545. IF=8.456

【11】T. Wu, J. Zhang, Y. Wang, B. Sun, M. Yin, G. L. Bowlin, X. Mo. Design and Fabrication of a Biomimetic Vascular Scaffold Promoting in Situ Endothelialization and Tunica Media Regeneration. ACS Applied Bio Materials, 1 (2018), 833-844.

【10】T. Wu, J. Zhang, Y. Wang, D. Li, B. Sun, H. El-Hamshary, M. Yin, X. Mo. Fabrication and Preliminary Study of a Biomimetic Tri-Layer Tubular Graft Based on Fibers and Fiber Yarns for Vascular Tissue Engineering, Materials Science and Engineering C, 82 (2018), 121-129. IF=4.959

【9】T. Wu, H. Zheng, J. Chen, Y. Wang, B. Sun, Y. Morsi, H. El-Hamshary, S.S. Al-Deyab, C. Chen, X. Mo. Application of a Bilayer Tubular Scaffold Based on Electrospun Poly(L-lactide-co-caprolactone)/Collagen Fibers and Yarns for Tracheal Tissue Engineering, Journal of Materials Chemistry B, 5 (2017), 139-150. IF=5.047

【8】T. Wu, D. Li, Y. Wang, B. Sun, D. Li, Y. Morsi, H. El-Hamshary, S.S. Al-Deyab, X. Mo. Laminin-Coated Nerve Guidance Conduits Based on Poly(L-lactide-co-glycolide) Fibers and Yarns for Promoting Schwann Cells’ Proliferation and Migration, Journal of Materials Chemistry B, 5 (2017), 3186-3194. IF=5.047

【7】T. Wu, J. Zhang, Y. Wang, B. Sun, X. Guo, Y. Morsi, H. El-Hamshary, M. El-Newehy, X. Mo. Development of Dynamic Liquid and Conjugated Electrospun Poly (L-lactide-co-caprolactone)/Collagen Nanoyarns for Regulating Vascular Smooth Muscle Cells Growth, Journal of Biomedical Nanotechnology, 13 (2017), 303-312. IF=5.068

【6】T. Wu, B. Sun, D. Li, X. Mo. Anti-CD133 Antibody Loaded Bilayer Tubular Scaffold Based on Poly(L-lactide-co-caprolactone)/Collagen Nanofibers and Nanoyarns for Vascular Tissue Engineering, Journal of Controlled Release, 259 (2017), e129. (Conference Abstract). IF=7.90

【5】B. Sun^#, T. Wu^#, J. Wang, D. Li, J. Wang, Q. Gao, M.A. Bhutto, H. El-Hamshary, S.S. Al-Deyab, X. Mo. Polypyrrole-Coated Poly(L-lactic acid-co-ε-caprolactone)/Silk Fibroin Nanofibrous Membranes Ppromoting Neural Cell Proliferation and Differentiation with Electrical Stimulation, Journal of Materials Chemistry B, 4 (2016), 6670-6679. (Equal Contribution) IF=5.047

【4】T. Wu, B. Jiang, Y. Wang, A. Yin, C. Huang, S. Wang, X. Mo. Electrospun Poly(L-lactide-co-caprolactone)–Collagen–Chitosan Vascular Graft in a Canine Femoral Artery Model, Journal of Materials Chemistry B, 3 (2015), 5760-5768. IF=5.047

【3】T. Wu, C. Huang, D. Li, A. Yin, W. Liu, J. Wang, J. Chen, H. Ei-Hamshary, S.S. Al-Deyab, X. Mo. A multi-layered vascular scaffold with symmetrical structure by bi-directional gradient electrospinning, Colloids and Surfaces, B: Biointerfaces, 133 (2015), 179-188. IF=3.973

【2】T. Wu, C. Huang. J. Chen, W. Liu, X. Mo. Fabrication of Multi-layered composite scaffolds by bi-directional electrospinning method, Journal of Donghua University (Eng. Ed.), 31 (2014), 718-722.

【1】T. Wu, C. Huang. X. Mo. A new vascular tissue engineering material: Electrospun small-diameter nanofibous scaffolds. Chinese Journal of Tissue Engineering Research, 17 (2013), 5387-5394.

已发表英文论著

【1】  X. Mo, B. Sun, T. Wu, D. Li. Electrospun Nanofibers for Tissue Engineering. In: Electrospinning: Nanofabrication and Applications, William Andrew Publishing, pp719-734, 2019, ISBN 978-0-323-51270-1, DOI: 10.1016/B978-0-323-51270-1.00024-8.

【2】X. Mo, T. Wu, B. Sun, EI-Hamshary H. Nanofiber composities in tendon tissue engineering. In: Murugan Ramalingam and Seeram Ramakrishna(ED), Nanofiber Composites for Biomedical Application, Woodhead Publishing, pp345-368, 2017, ISBN 978-0-08-100173-8 (print), ISBN 978-0-08-100208-7 (online).

【3】X. Mo, B. Sun, T. Wu, H. EI-Hamshary. Nanofiber composities in neural tissue engineering. In: Murugan Ramalingam and Seeram Ramakrishna(ED), Nanofiber Composites for Biomedical Application, Woodhead Publishing, pp395-410, 2017, ISBN 978-0-08-100173-8 (print), ISBN 978-0-08-100208-7 (online).

已授权专利

1.莫秀梅, 吴桐，王元非，李丹丹. 一种仿生天然血管三层结构的复合材料血管支架及其制备方法, 发明专利，授权号：ZL 201610638328.5.

2.莫秀梅, 吴桐，王元非, 李丹丹，孙彬彬.一种 PLGA 三维神经导管及其制备方法, 发明专利，授权号：ZL 201610584672.0.

3.莫秀梅, 吴桐，王元非. 一种肝素与双生因子协同调控的 P(LLA-CL)/胶原蛋白双层血管支架的制备方法,发明专利, 授权号：ZL 201510749818.8.

4.莫秀梅, 吴桐，王元非. 一种聚乳酸己内酯-胶原蛋白双层仿生血管支架的制备方法, 发明专利，授权号：ZL 201510640661.5.

5.莫秀梅，吴桐，黄晨. 一种乳酸己内酯共聚物/胶原蛋白/壳聚糖小口径纳米纤维血管支架的制备方法, 发明专利，授权号：ZL 201310231921.4。

联系方式

邮箱：tongwu24@163.com，招收生物材料学、生物学、基础医学、临床医学、纺织科学、材料学等相关专业和研究方向的全职和在职博士后。