个人简介
2010年毕业于山东师范大学,2016年毕业于中科院上海生物化学与细胞生物学研究所,获理学博士学位(硕博连读),2016-2018年于协和医学院进行博士后训练,2019年初入职青岛大学医学部神经再生与康复研究院。长期从事脑损伤与修复的免疫调控机制研究。目前以第一作者及通讯作者在Journal of Experimental Medicine,Cell Reports,Brain Behavior and Immunity,Journal of Neuroinflammation等国际知名杂志发表论文十余篇。担任山东省高等学校青创团队“脑神经损伤和修复的免疫调控研究”负责人;青岛市脑疾病治疗可穿戴智能设备技术创新中心核心成员;主持国自然项目1项、山东省青创团队科技计划项目1项、核心参与国家重点研发项目1项;担任多个杂志编委及审稿人。
研究方向
神经免疫,主要聚焦多发性硬化、缺血性脑损伤及帕金森病过程中神经损伤与修复的免疫调控机制开展研究,具体包括:
(1)T细胞调控脑损伤和修复的作用及机制
(2)小胶质细胞介导神经炎症起始及消退的机制
代表性论文
1. Zhou X, Zhao R, Lv M, Xu X, Liu W, Li X, Go Y, Zhao Z, Zhang Z, Li Y, Xu R, Qi W, Cui Y*. ACSL4 promotes microglia-mediated neuroinflammation by regulating lipid metabolism and VGLL4 expression. Brain Behavior and Immunity. 2023; 109: 331-343. IF=15.1
2. Cui Y, Zhang Y, Zhao X, Shao L, Liu G, Sun C, Xu R, Zhang Z*. ACSL4 exacerbates ischemic stroke by promoting ferroptosis-induced brain injury and neuroinflammation. Brain Behavior and Immunity. 2021; 93: 312-321. IF=15.1 (ESI高被引论文)
3. Sun X#, Cui Y#, Feng H, Liu H, Liu X*. TGF-beta signaling controls Foxp3 methylation and T reg cell differentiation by modulating Uhrf1 activity. Journal of Experimental Medicine. 2019; 216: 2819-2837. IF=17.58 (co-first author)
4. Cui Y, Chen X, Zhang J, Sun X, Liu H, Bai L, Xu C, Liu X*. Uhrf1 Controls iNKT Cell Survival and Differentiation through the Akt-mTOR Axis. Cell Reports. 2016; 15: 256-263. IF=9.995
5. Cui Y, Zhang Z, Zhou X, Zhao Z, Zhao R, Xu X, Kong X, Ren J, Yao X, Sun J, Wen Q, Gu F, Gao S, Wan Q*. Microglia and Macrophage Exhibit Attenuated Inflammatory Response and Ferroptosis Resistance after RSL3 Stimulation via Increasing Nrf2 Expression. Journal of Neuroinflammation.2021; 18(1):249. IF=9.59
联系方式
邮箱:cuiyu@qdu.edu.cn