简介
罗倩,博士,青年卓越人才。2017年硕士毕业于山东大学药学专业。 2022年博士毕业于荷兰马斯特里赫特大学基础医学专业。2022年入职青岛大学医学部神经再生与康复研究院。从事阿尔茨海默病机理与干预的研究,主要包括阿尔茨海默病的免疫调控机制、脂质代谢调控及药物开发研究。目前以第一作者在国际知名杂志发表论文多篇,主持国家自然科学基金项目1项,担任多个杂志编委及审稿人。
研究方向
阿尔茨海默病中小胶质细胞的作用机制研究,鞘脂代谢紊乱对阿尔茨海默病的调控机制研究,潜在治疗阿尔茨海默病的活性药物开发等研究。
代表性学术论文
1. Simone M. Crivelli, Qian Luo*, Daan van Kruining, Caterina Giovagnoni, Marina Man´e-Damas , Sandra den Hoedt , Dusan Berkes , Helga E. De Vries, Monique T. Mulder , Jochen Walter , Etienne Waelkens , Rita Derua , Johannes V. Swinnen , Jonas Dehairs , Erwin P.M. Wijnands , Erhard Bieberich , Mario Losen , Pilar Martinez- Martinez FTY720 decreases ceramides levels in the brain and prevents memory impairments in a mouse model of familial Alzheimer’s disease expressing APOE4. Biomedicine & Pharmacotherapy 2022 (IF:7.419, 中科院1区)
2. Simone Mwenda Crivelli*, Qian Luo*, Jo Stevens, Caterina Giovagnoni, Daan van Kruining, Gerard Bode, Sandra den Hoedt, Barbara Hobo, Anna-Lena Scheithauer, Jochen Walter, Monique T Mulder, Christopher Exley, Michelle M. Mielke, Helga E De Vries, Kristiaan Wouters, Daniel L.A. van den Hove, Dusan Berkes, María Dolores Ledesma, Joost Verhaagen, Mario Losen, Erhard Bieberich, Pilar Martinez-Martinez CERTL Reduces C16 Ceramide, Amyloid-β Levels and Inflammation in a Model of Alzheimer's Disease. Alzheimer disease & therapy 2021 (IF:6.116, 中科院2区)
3. Daan van Kruining*, Qian Luo*, Gerhildvan Echten Deckert, Michelle M.Mielke, Andrew Bowman, Shane Ellis, Tiago Gil Oliveira, Pilar Martinez-Martinez Sphingolipids as prognostic biomarkers of neurodegeneration, neuroinflammation, and psychiatric diseases and their emerging role in lipidomic investigation methods. Advanced Drug Delivery Reviews 2020 (IF:15.47, 中科院1区)
4. Shanshan Wang*, Qian Luo*, and Peihong Fan Cannabisin F from Hemp (Cannabis sativa) Seed Suppresses Lipopolysaccharide-Induced Inflammatory Responses in BV2 Microglia as SIRT1 Modulator. Int J Mol Sci 2019 (IF:5.923, 中科院2区)
5. Shanshan Wang*, Qian Luo*, Yuefang Zhou, and Peihong Fan CLG from Hemp Seed Inhibits LPS-Stimulated Neuroinflammation in BV2 Microglia by Regulating NF-κB and Nrf 2 Pathways. ACS Omega 2019 (IF: 3.512, 中科院3区)
6. Qian Luo, Xiaoli Yan, Larisa Bobrovskaya, Mei Ji, Huiqing Yuan, Hongxiang Lou, Peihong Fan Anti-neuroinflammatory effects of grossamide from hemp seed via suppression of TLR-4-mediated NF-κB signaling pathways in lipopolysaccharide-stimulated BV2 microglia cells. Mol Cell Biochem 2017 (IF:3.396, 中科院3区)
联系方式
邮箱: luoqian_qdu@126.com