研究方向
毕业于中国医学科学院北京协和医学院。从事心脑血管药理学（卒中、精神类疾病焦虑抑郁、动脉粥样硬化、高血脂）相关研究，开展新药研制并探讨其分子机制。主要围绕药理学方向展开中药及其主要成分调控线粒体、防治缺血性脑卒中神经损伤的研究，并揭示其对缺血性脑卒中的防治作用及分子机制。围绕神经干细胞与缺血性脑卒中之间的关系，开展药物调控神经干细胞、促进缺血性脑卒中后神经修复的研究，深入探索药物促进神经干细胞增殖分化、修复缺血受损脑神经系统的分子机制。增进对缺血性脑卒中发病分子机制的认知，促进治疗缺血性脑卒中药物的开发。主持国家级、省级科研项目3项，在高水平国际杂志发表学术论文20余篇。
E-mail：zhuting0402@126.com
主持项目
1.国家自然科学基金青年项目：人参皂苷Rb3调控AMPK/OPA1信号通路促进神经干细胞增殖和分化治疗缺血性脑卒中的分子机制研究
2.山东省自然科学基金青年项目：三七皂苷R1激活NAMPT-NAD+轴调控神经再生抗缺血性脑卒中分子机制研究
3.山东省医药卫生科技发展计划项目：基于CC-ABPP技术探究丁苯酞促进神经再生抗缺血性脑卒中的分子靶标
代表性学术论文
1.Ting Zhu, Lei Wang, Liping Wang and Qi Wan*. Therapeutic targets of neuroprotection and neurorestoration in ischemic stroke: Applications for natural compounds from medicinal herbs. Biomedicine & Pharmacotherapy. 148 (2022) 112719.（IF=7.419, ESI高被引论文）
2. Xiaodi Xie, Lei Wang, Shanshan Dong, ShanChun Ge, Ting Zhu*. Immune regulation of the gut-brain axis and lung-brain axis involved in ischemic stroke. Neural Regeneration Research. 2024 Mar;19(3):519-528.（IF=6.1, ESI高被引论文）
3.Weijie Xie#, Ting Zhu#, Shuxia Zhang, et al.. Protective effects of Gypenoside XVII against cerebral ischemia/reperfusion injury via SIRT1-FOXO3A- and Hif1a-BNIP3-mediated mitochondrial autophagy. J Transl Med. 2022, 20(1): 622.（IF=8.440）
4.Ting Zhu, Weijie Xie, Lei Wang, et al.. Notoginsenoside R1 activates NAMPT-NAD+-SIRT1 cascade to promote post-ischemic angiogenesis by modulating Notch signalling. Biomedicine & Pharmacotherapy. 140 (2021) 111693.（IF=7.419）
5.Ting Zhu, Lei Wang, Weijie Xie, et al.. Notoginsenoside R1 improves cerebral ischemia/reperfusion injury by promoting neurogenesis via the BDNF/Akt/CREB pathway. Frontiers in Pharmacology. 2021, 12:615998.（IF=5.998）
6.Ting Zhu, Lei Wang, Fang Tian, et al.. Anti-ischemia/reperfusion injury effects of notoginsenoside R1 on small molecule metabolism in rat brain after ischemic stroke as visualized by MALDI-MS imaging. Biomedicine & Pharmacotherapy 129 (2020) 110470.（IF=7.419）
7.Ting Zhu, Lei Wang, Yicheng Feng, et al.. Classical Active Ingredients and Extracts of Chinese Herbal Medicines：Pharmacokinetics, Pharmacodynamics and Molecular Mechanisms for Ischemic Stroke. Oxidative Medicine and Cellular Longevity,Volume 2021, Article ID8868941, 27 pages.（IF=7.3）
8. Ting Zhu#, Shanshan Dong#, Na Qin, et al..Dl-3-n-butylphthalide attenuates cerebral ischemia/reperfusion injury in mice through AMPK-mediated mitochondrial fusion. Frontiers in Pharmacology, 2024 Feb 22:15:1357953.（IF=5.988）
9.Ting Zhu, Xiang-Bao Meng, Dong-Xia Dong, et al.. Xuesaitong injection (lyophilized) combined with aspirin and clopidogrel protect against focal cerebral ischemic/reperfusion injury in rats by suppressing oxidative stress and inflammation and regulating the NOX2/IL-6/STAT3 pathway. Annals of Palliative Medicine, 2021, apm-20-1681.（IF=2.595）
10.Ting Zhu, Bin-Yu Fang, Xiang-Bao Meng, et al.. Folium Ginkgo Extract and Tertram Ethypyrazine Sodium Chloride Injection (FT injection) protects against focal cerebral ischemia/reperfusion injury via activating the Akt/Nrf2 pathway and inhibiting NLRP3 inflammasome activation. Pharmaceutical Biology.（IF=3.503）
11.Xiang-Bao Meng#,Ting Zhu#, De-Hui Yang, et al.. Xuezhitong capsule, an extract of Allium macrostemon Bunge, exhibits reverse cholesterol transport and accompanies high-density lipoprotein levels to protect against hyperlipidemia in ApoE−/−mice. Annals of Translational Medicine, 2019, 7 (11): 239.（IF=3.59）
